SAM-e (S-Adenosylmethionine) is an amino acid derivative that has undergone dozens of trials involving thousands of patients and has been clinically proven to benefit brain and joint function. Found in all living cells, SAM-e is also called activated methionine (an essential amino acid) since it is formed by the combining of ATP with methionine. SAM-e 400 is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product. It is made naturally by microbiological fermentation and then specially processed to preserve 68-80% (S,S) SAM-e, the highest active level available.
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